
Motherwort
Leonurus cardiaca
Key Compounds
- Leonurine
- Leonurinine
- Stachydrine
- Betonicine
- Turicin
- Rutin
- Quercetin
- Hyperoside
- Caffeic acid
- Chlorogenic acid
- Lavandulifolioside
- Leocardin
- Iridoids
Traditional Use
- Heart palpitations from anxiety — the most specific traditional indication: rapid or irregular heart action caused by anxiety, stress, or nervous tension; leonurine has negative chronotropic effects (slows heart rate) in animal models; German Commission E approved for 'cardiac disorders associated with anxiety states'
- Postpartum uterine recovery — 益母草 (yìmǔcǎo) in Chinese medicine: used postpartum to help the uterus contract and return to normal size; stachydrine has uterotonic activity; this is the primary Chinese indication and the source of the Chinese name 'mother benefit herb'
- Menstrual regulation — traditional European and Chinese use for delayed menstruation (emmenagogue) and painful periods; the uterotonic alkaloids stimulate uterine muscle; used in the weeks preceding menstruation for dysmenorrhoea management
- Anxiety as physical symptom — in the herbal medicine tradition, motherwort specifically addresses the overlap between anxiety and cardiovascular symptoms: the racing heart, chest tightness, and palpitations that occur during anxiety episodes; it works on both the cardiac rhythm and the nervous system simultaneously
- Thyroid-associated palpitations — some European herbal practitioners use motherwort for palpitations associated with hyperthyroidism; the negative chronotropic effect provides symptomatic relief while underlying thyroid condition is treated; this is an off-label traditional use without strong clinical trial support
- Traditional Chinese medicine — 益母草 (yìmǔcǎo): one of the most important herbs in Chinese gynaecological medicine; listed in the Chinese Pharmacopoeia; used in hundreds of traditional formulas for postpartum haemorrhage, uterine inertia, irregular menstruation, and dysmenorrhoea

The genus name is Leonurus — lion-tail.
The species name is cardiaca — heart.
The plant was named lion-tail-heart. This is not metaphor. The deeply lobed leaves look like a lion’s tail. The species name points directly to the cardiac application. When Linnaeus formalised the binomial in 1753, the plant’s primary medical use was already well-known — he encoded it in the name.
The Chinese named it 益母草 (yìmǔcǎo): mother benefit herb. German herbalists called it Herzgespann: heart anchor. Three languages, three centuries of documentation, two main uses. The same two uses in every tradition.
Meet the plant
A perennial herb, 60–120 cm tall, with deeply palmately lobed leaves and small pink-white labiate flowers arranged in whorls up the square stem. Strongly bitter to taste. In the mint family.
It grows in disturbed ground, hedgerows, roadsides, and waste places throughout temperate Europe and Asia. It grows wherever it is not deliberately cultivated and in some places where it is.
| Detail | |
|---|---|
| Family | Lamiaceae |
| Species | Leonurus cardiaca |
| Also called | Herzgespann (German, ‘heart anchor’); メハジキ (mehajiki, Japan, L. japonicus); 益母草 (yìmǔcǎo, China) |
| Life cycle | Perennial herb |
| Native range | Central and Eastern Europe, Central Asia; naturalised in North America |
| Part used | Aerial parts (leaves and flowers, dried) |
The two uses
Two applications appear consistently across European, Chinese, and American herbal traditions, documented independently:
Heart palpitations from anxiety. The specific indication is the racing heart during anxiety — the cardiac symptom of nervous tension. Not organic heart disease. Not arrhythmia requiring pharmaceutical management. The acute physical expression of stress in the cardiovascular system. German Commission E approved motherwort specifically for ‘cardiac disorders associated with anxiety states.’
Postpartum uterine recovery and menstrual irregularity. Chinese medicine uses 益母草 (yìmǔcǎo) postpartum to help the uterus contract back to normal size and expel retained tissue. European tradition uses it for delayed menstruation and menstrual pain. Both are uterotonic applications — stimulating uterine smooth muscle.
The alkaloid leonurine — unique to the Leonurus genus — provides the pharmacological basis for both. It slows the heart rate (negative chronotropic effect) and stimulates uterine smooth muscle contraction (uterotonic effect). The same alkaloid, acting on smooth muscle in two different organs, produces two different beneficial effects depending on the clinical context.
The smooth muscle explanation
Smooth muscle is not under conscious control. It is in the heart, uterus, blood vessels, digestive tract, and airways. Leonurine modulates smooth muscle tone generally, with different effects at different doses and in different tissues.
At the cardiovascular level: reduces heart rate and mildly dilates blood vessels. This reduces the palpitation and gives the anxious heart somewhere to settle.
At the uterine level: stimulates contraction. This is the postpartum application — helping the uterus return to normal size. This is also why motherwort is contraindicated in pregnancy: the uterotonic effect that is beneficial postpartum is dangerous during gestation.
Stachydrine (a betaine alkaloid also found in the plant) adds to the uterotonic activity.
| Compound | Class |
|---|---|
| Leonurine | Guanidine alkaloid |
| Leonurinine | Alkaloid |
| Stachydrine | Betaine alkaloid |
| Betonicine | Betaine alkaloid |
| Turicin | Alkaloid |
| Rutin | Flavonol glycoside |
| Quercetin | Flavonol |
| Hyperoside | Flavonol glycoside |
| Caffeic acid | Hydroxycinnamic acid |
| Chlorogenic acid | Polyphenol |
| Lavandulifolioside | Phenylethanoid glycoside |
| Leocardin | Terpenoid |
| Iridoids | Terpenoid glycosides |
What people actually do with it
Tincture (primary preparation — very bitter as tea): 2–4 mL, 2–3 times daily. The bitter taste of the dried herb is strong enough that tincture is usually preferred over tea. Used for anxiety-related palpitations and menstrual regulation.
Tea (if bitter taste is acceptable): 1–2 teaspoons dried aerial parts, steeped 15–20 minutes, 2–3 cups daily. Combine with honey or other herbs to offset the bitterness.
For acute palpitations: Taken at the first sign of symptoms. The action is relatively rapid — typically within 20–30 minutes.
For menstrual regulation: Begun 1–2 weeks before menstruation. Not taken during pregnancy under any circumstances.
Often combined with: Hawthorn (for cardiovascular conditions), passionflower (for anxiety), valerian (for nervous system support).
Could you grow this yourself?
Easily. Motherwort grows in almost any soil in sun to partial shade. It self-seeds readily and spreads. In good conditions it becomes vigorous and requires management.
Harvest aerial parts when the lower whorls of flowers are just opening for highest alkaloid content. Dry quickly.
The bitter taste when harvesting and drying is pronounced. The smell is distinctive — herbal, slightly pungent.
Motherwort (メハジキ) in Japan
Japan has a native Leonurus species: Leonurus japonicus (メハジキ, mehajiki), which grows wild throughout Japan in disturbed habitats. It contains the same primary alkaloids as the European species. In traditional Japanese folk medicine, メハジキ has been used for gynaecological conditions — irregular menstruation, postpartum recovery — in direct parallel to the Chinese and European applications.
The Chinese 益母草 (yìmǔcǎo) is Leonurus japonicus — the same species as Japanese メハジキ. This plant is listed in the Chinese Pharmacopoeia and is used in numerous classical Chinese formulas for gynaecological conditions. Japanese kampo practitioners who use it follow the Chinese pharmacopoeia tradition.
The plant is available in Japan through kampo dispensaries and as a Western herbal supplement. It is not as prominent as the major kampo herbs but has genuine traditional standing in Japanese folk medicine through the native species.
Things you’re probably wondering
Why is it called motherwort? Traditional use in women’s health — postpartum recovery, menstrual regulation, calming anxious new mothers. Three languages named it for the same applications: English (motherwort), German (Herzgespann = heart anchor), Chinese (益母草 = mother benefit herb).
Is it safe during pregnancy? No. The uterotonic alkaloids stimulate uterine contraction and can cause miscarriage or premature labour. Contraindicated throughout pregnancy. Used postpartum, not during gestation.
What is leonurine? An alkaloid unique to the Leonurus genus. Slows heart rate (negative chronotropic) and stimulates uterine contraction (uterotonic). The same alkaloid provides the pharmacological basis for both main traditional applications.
Can it be used for actual arrhythmia? Only under professional supervision. The cardiac application in traditional medicine is specifically anxiety-related palpitations in otherwise healthy hearts — not organic arrhythmia requiring pharmaceutical management.
Botanical details
| Field | Detail |
|---|---|
| Family | Lamiaceae |
| Species | Leonurus cardiaca L. (European); L. japonicus Houtt. (Chinese/Japanese) |
| Related species | L. japonicus (益母草, メハジキ — used in China and Japan) |
| Life cycle | Perennial herb |
| Native range | C. and E. Europe, C. Asia; L. japonicus from E. Asia |
| Major producers | Eastern Europe; China |
| Japan | メハジキ (L. japonicus) — native species, folk medicine use; Chinese 益母草 in kampo context |
| Part used | Aerial parts (leaves and flowers) |
The full compound list
| Compound | Class |
|---|---|
| Leonurine | Guanidine alkaloid |
| Leonurinine | Piperidine alkaloid |
| Stachydrine | Betaine alkaloid |
| Betonicine | Betaine alkaloid |
| Turicin | Alkaloid |
| Rutin | Flavonol glycoside |
| Quercetin | Flavonol |
| Hyperoside | Flavonol glycoside |
| Kaempferol | Flavonol |
| Caffeic acid | Hydroxycinnamic acid |
| Chlorogenic acid | Polyphenol |
| Lavandulifolioside | Phenylethanoid glycoside |
| Leocardin | Terpenoid |
| Ajugol | Iridoid glycoside |
| Leonuride | Iridoid glycoside |
| Ursolic acid | Pentacyclic triterpenoid |
| Oleanolic acid | Pentacyclic triterpenoid |
| Tannins | Polyphenols |
See Also
- Hawthorn — primary cardiovascular herb; often combined with motherwort for cardiac conditions
- Passionflower — complementary anxiolytic for anxiety-related palpitations
- Valerian — nervous system calming; combined in anxiety-with-palpitations presentations
References
- Shikov, A.N. et al. (2011). Leonurus cardiaca: a review. Phytomedicine, 18(14), 1202–1210.
- Ritter, M. et al. (2010). Leonurine and stachydrine in motherwort. Phytomedicine, 17(5), 381–385.
- Wojtyniak, K. et al. (2013). Leonurus cardiaca — pharmacological effects. Phytotherapy Research, 27(8), 1115–1120.
- Ho, Y.L. et al. (2011). Anti-inflammatory and antinociceptive activities of Leonurus japonicus. Journal of Ethnopharmacology, 133(2), 717–721.